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The mild form can cause hemolytic anemia, with such symptoms as fatigue, pale skin, lightheadedness, and shortness of breath

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In a study of 83 men with obesity, insulin resistance, and symptoms of low testosterone (including erectile dysfunction), those treated with tirzepatide for just two months saw significantly greater improvements than those receiving traditional testosterone replacement therapy (TRT) or lifestyle changes alone

Microglia exhibit phenotypic plasticity, capable of transitioning between the pro-inflammatory M1 phenotype and the anti-inflammatory M2 phenotype (Qiao et al., 2023)

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